Quick Answer: Is Zoloft Bad For Your Liver?

Which antidepressant is easiest on the liver?

The antidepressants that seem to have the least potential for hepatotoxicity are citalopram, escitalopram, paroxetine, and fluvoxamine..

Do antidepressants harm your liver?

Some antidepressants can damage your liver over time, including monoamine oxidase (MAO) inhibitors, tricyclic or tetracyclic antidepressants, bupropion, duloxetine and agomelatine. Antidepressant drugs with a lower risk of liver damage include citalopram, escitalopram, paroxetine and fluvoxamine.

Which antidepressant is safe in liver disease?

For patients with CLD and hepatitis C, selective serotonin reuptake inhibitors (SSRIs) appear to be the safest class of antidepressants.

Is 50mg of Zoloft a lot?

The maximum dose of Zoloft is 200 mg per day (which can be taken as two 100 mg tablets). Most studies suggest that the most effective dose of Zoloft is 50 mg per day. This dose is proven to be the most effective and tolerable dose for most patients.

What drugs are bad for the liver?

The 10 Worst Medications for Your Liver1) Acetaminophen (Tylenol) … 2) Amoxicillin/clavulanate (Augmentin) … 3) Diclofenac (Voltaren, Cambia) … 4) Amiodarone (Cordarone, Pacerone) … 5) Allopurinol (Zyloprim) … 6) Anti-seizure medications. … 7) Isoniazid. … 8) Azathioprine (Imuran)More items…•Feb 11, 2019

Is Trazadone hard on your liver?

Trazodone may cause alteration of liver enzyme levels at normal doses, but elevations are usually modest and usually do not require dose modification or discontinuation. Rare instances of ALF and death from trazodone have been described.

Is Zoloft safe for the liver?

Effects on the liver People with liver failure can take Zoloft, but doctors may need to adjust the dosage. If someone has mild liver failure, the doctor will prescribe half the usual dosage, for example. Doctors will not prescribe Zoloft to anyone with moderate or severe liver failure.

What are signs of unhealthy liver?

If signs and symptoms of liver disease do occur, the may include:Skin and eyes that appear yellowish (jaundice)Abdominal pain and swelling.Swelling in the legs and ankles.Itchy skin.Dark urine color.Pale stool color.Chronic fatigue.Nausea or vomiting.More items…•Feb 21, 2020

Which painkiller is easiest on the liver?

Acetaminophen is broken down by the liver and can form byproducts that are toxic to the liver, so this warning is not completely without merit. But take it from a hepatologist, acetaminophen is the best option for pain relief for people with liver disease.

Can antidepressants cause fatty liver disease?

Medications commonly implicated in causing fatty liver include corticosteroids, antidepressant and antipsychotic medications and, most commonly, tamoxifen.

Is Zoloft metabolized by the liver?

ZOLOFT is extensively metabolized by the liver. In patients with chronic mild liver impairment, sertraline clearance was reduced, resulting in increased AUC, Cmax and elimination half-life. The effects of sertraline in patients with moderate and severe hepatic impairment have not been studied.

Why is Zoloft bad for you?

Taking Zoloft may put you at risk for a rare, but possibly life-threatening condition called serotonin syndrome. This risk is higher if you are also taking other serotonin-related medications like triptans (a common migraine medication), tricyclic antidepressants, or the pain medication Ultram (tramadol).